Program and schedule

Sunday, June 16th, 2019

Christian Hackenberger (Leibniz Research Institute for Molecular Pharmacology and Humboldt University of Berlin)
Welcome and Introductory Remarks
Annette Beck-Sickinger (University of Leipzig)
Ligand binding, signaling and trafficking
Philip Dawson (The Scripps Research Institute, La Jolla)
Customizing macromolecules through chemical ligation
Dinner/Reception (Planck Lobby)


Monday, June 17th, 2019

Anne Conibear (The University of Queensland)
Richard Payne (University of Sydney)
Rapid Protein Synthesis using Diselenide-Selenoester Ligation Chemistry
Norman Metanis (Hebrew University Jerusalem)
Employing Chemical Protein Synthesis for Human Selenoproteins Functional Characterizations
Xuechen Li (University of Hong Kong)
New strategies for protein chemical synthesis and peptide cyclization
Bradley Pentelute (MIT)
Total chemical synthesis of proteins in hours
Coffee Break
Claudia Bello (University of Florence)
Itaru Hamachi (Kyoto University)
Selective protein modification by ligand-directed chemistry
Yaowen Wu (Umea University)
Chemo-optogenetic control of protein function in live cells
Aymelt Itzen (Medical University Hamburg)
Insights into the biochemistry of protein phosphorylcholination
Mark Howarth (Oxford University)
Spy and Snoop peptide superglues applied to nutrition and global health
Stephan Pless (University of Copenhagen)
Philip Cole (Harvard Medical School)
AKTivation Mechanisms
Champak Chatterjee (University of Washington)
Chemical approaches to investigate eukaryotic gene transcription
Henning Mootz (University of Münster)
New Tools for Protein Ligation and Light Control
Tom Muir (Princeton University)
Painting Chromatin with Synthetic Protein Chemistry
Group picture
Christian Hackenberger (FMP and HU Berlin)
Poster Session A and Coffee Break (Meitner and Goethe Hall)
Rising Stars
Kathrin Lang (TU Munich)
Expanding the genetic code - protein chemistry in living systems
Yael David (Memorial Sloan Kettering Cancer Center)
Engineering chromatin states towards understan- ding epigenetic regulation
Hannes Mikula (TU Vienna)
Exit the cube: Advancing bioorthogonal bond-cleavage reactions to the next level
Satpal Virdee (University of Dundee)
Semisynthetic Protein Sensors of Ubiquitin E3 Ligase Activity
Yongxiang Chen (Tsinghua University)
Synthesis of lipidated and phosphorylated proteins
Monika Raj (Auburn University)
Secondary Amine Selective Peptide (SASP) Bioconjugation


Tuesday, June 18th, 2019

Chair Eoin Scanlan (Trinity College Dublin)
Yasuhiro Kajihara (Osaka University)
Functions of N-Glycan on Protein
Carlo Unverzagt (University of Bayreuth)
Synthesis of Glycoforms of Human Erythropoietin
Hilal Lashuel (EPFL Lausanne)
How synthetic proteins are redefining our understanding of neurodegenerative diseases
James Petersson (University of Pennsylvania)
Parkinson‘s Disease studies enabled by protein semi-synthesis
Coffee Break (Meitner Hall)
Huan Wang (Nanjing University)
Hiroaki Suga (University of Tokyo)
From Constrained Peptides to NeoBiologics
Adel ElSohly (Genentech Harnessing)
Protein Synthesis Techniques for Immune Monitoring
Dirk Schwarzer (University of Tübingen)
Establishing sortase-catalyzed multi-peptide assemblies
Heinrich Leonhardt (LMU Munich)
Site-specific functionalization of proteins for research and therapeutic applications
Frank Bordusa (University of Halle)
TrypCo Technology: A versatile enzymatic tool for site-specific generation of ADC’s
Lunch Break (Restaurant)
Excursion: Science History in Berlin-Dahlem
Nicolas Rasche (Merck) and Marc-Andre Kasper (FMP)
Kristian Stromgaard (University of Copenhagen)
Targeting receptor complexes: Exploring protein-protein interactions by protein semisynthesis
Christina Schroeder (University of Queensland)
Rethinking inhibition of sodium channels for therapeutic purposes
Thomas Hoeg-Jensen (Novo Nordisk)
Long recombinant homogeneous linkers for dual protein conjugations, to replace heterogeneous PEG
Huan Wang (Nanjing University)
Chemical Modification and Macrocyclization of Peptides
Norbert Sewald (University of Bielefeld)
Twofold bio-orthogonal derivatization of proteins by different formylglycine-generating enzymes
Harald Kolmar (TU Darmstadt)
Chemoenzymatic approaches for the cell-specific delivery of dextran-loaded cytotoxic cargoes
Christian Hackenberger (FMP and HU Berlin)
Poster Session B with Snacks (Meitner and Goethe Hall)


Wednesday, June 19th, 2019

Suwei Dong (Peking University)
Christian Becker (University of Vienna)
Semisynthesis of membrane-associated proteins
Hironobu Hojo (Osaka University)
Chemical synthesis of proteins with post-translational modifications
Oliver Seitz (Humboldt University of Berlin)
Peptide-templated Live Cell Protein Labeling
Lei Liu (Tsinghua University)
Development of ubiquitin probes using chemical protein synthesis
Coffee Break (Meitner Hall)
Olalla Vazquez (University of Marburg)
Helma Wennemers (ETH Zurich)
From Selective Intermolecular Interactions to Metal-Nanoparticles
Christof Niemeyer (Karlsruhe Institute of Technologie)
Nano- and Microstructured Protein Assemblies for Biotechnological Applications
Richard Wombacher (Heidelberg University)
Fluorogenic Probes for Bioorthogonal Chemistry - Live Cell Imaging and Single Molecule Localization Microscopy
Valentin Wittmann (University of Konstanz)
Application of the Inverse-Electron-Demand Diels-Alder Reaction in Metabolic Glycoengineering
Lunch Break (Restaurant)
Louise Walport (The Crick Institute)
Jason Chin (MRC LMB, Cambridge)
Reprogramming the Genetic Code
Edward Lemke (University of Mainz)
Semi-synthetic tools to decode plasticity in the dark proteome
Andreas Marx (University of Konstanz)
Chemical Biology and the Information beyond the Genome Sequence
Joseph Fox (University of Delaware)
Methods for Fast and Inducible Bioorthogonal Chemistry
Coffee Break (Meitner Hall)
Markus Muttenthaler (University of Vienna)
Jeffrey Bode (ETH Zurich)
Protein Synthesis with the KAHA Ligation
Ronald Raines (MIT)
Ghost Proteins
Ashraf Brik (Technion Haifa)
Palladium in Protein Synthesis
Transfer to Gala Dinner at Naturkunde Museum (Natural History Museum)
Gala Dinner and Poster Awards